CASE STUDY ᕤ Singing stress: 78% from 9 to 2. ᕥ 20% left are from extra-oral (including social and lifestyle) factors beyond dentist’s scope of practice. A deficient maxilla is the cardi-nal feature of Impaired Mouth Syndrome: a vast set of medical, dental and mood symptoms in both adults and children arising from a structurally impaired mouth. 34 Take-Aways from SZ’s case: A. Clinical epigenetics can solve many issues during and after orthodontics. B. Clinical epigenetics comes with no pain, no drugs (nor side effects). C. Clinical epigenetics delivers a fully grown maxilla that is foun-dational for Best Face with wider airway. Maxilla’s orthopedic growth should precede orthodontic move-ment of teeth. Next, let’s apply clin-ical epigenetics proactively. Case #3 of HL: Epigenetics Proactively Provided HL was 9 years-old when her mom Katie, already in epigenetic treatment herself, requested an eval-uation. “HL has crowded teeth and weak chin, even though we eat a Nourishing Traditions Diet 35 at home and follow the teachings of Weston A. Price Foundation 36 to grow her jaws.” As with preceding cases, 3D Jaw Diagnostics forms the basis of customized oral appliance design for all cases, as taught by my mentors Drs. Jay Gerber, Rich Beis-tle, and Mr. Tom Magill. 37, 38, 39, 40, 41 Construction bite was taken based on this research: “Mandibular posture change precedes mandibu-lar condylar cartilage remodel-ing.” 42 Increased mRNA was found in mandibular condyle on the protruded side, and less mRNA on the retruded side. The point: decompressing the TMJ can facilitate gene expression. Figures 21-24 show the result of the 18 Summer 2023 JAOS