CASE STUDY Figure 30 A. Patient’s rating of presenting symptoms, using Subjective Units of Distress Scale. B. Objective Evidence, such as minimal airway cross-section (where collapse occurs to cause apnea), cephalometric benchmarks, and follow-up sleep test if applicable. C. Clinical Evidence: facial glow reflecting sleep quality, uplifted mood, more energy, and a happier patient --not only on the surface, but also from within. Discussion Clinical Epigenetics offers dentists a new option to help patents upgrade their whole-body health by restoring Impaired Mouth as of 2024. Clinical Epigenetics starts with a premise as the two cases have shown: diagnose Impaired Mouth Syndrome first. Then restore Impaired Mouth with necessary changes in the oral environment and behavior to bring on fuller gene expression. A dentist’s paradigm (mental software and belief system) can make a pivotal difference. Figure 29 lists the presenting symptoms of Brenda and Kim despite seeing their dentists for years. Note their long standing nature. Nonetheless, their genes at ages 61 and 51 were ready for epigenetic signals to switch them on. Brenda’s symptoms improved 53% after 10 months of Clinical Epigenetics, while Kim had 90% after 36 months. Clinical Epigenetics is painless for the patient and low stress for the provider. Other major differ-ences include: • Clinical Epigenetics is a 80/20 team work between patient implantation and doctor diag-nosis and WholeHealth treat-ment plan. Figure 31: For a downloadable pdf, please visit HolisticMouthSolutions.com used her renewed energy to take training after her day job and became a certified yoga and pilates instructor and thereby generated another income stream for herself. Criteria for Success Broad smile with straight teeth is a byproduct of Clinical Epigenetics, not the sole aim. More important criteria for total health include those listed so far, plus: • No appliance ever heals the patient all by itself. The "secret sauce" is the attending doctor's ability to upgrade 14 Winter 2024 JAOS